|Positive WB detected in
|Western Blot (WB)
|WB : 1:500-1:1000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
13623-1-AP targets TRIM15 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
|Host / Isotype
|Rabbit / IgG
|TRIM15 fusion protein Ag4533
|tripartite motif-containing 15
|Calculated molecular weight
|465 aa, 52 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
TRIM15 (Tripartite motif-containing protein 15) is also named as RNF93, ZNF178, ZNFB7 and belongs to the TRIM/RBCC family. It acts as an ubiquitin-protein ligase and contributes to the endogenous restriction of retroviruses in cells.
Nat Cell Biol
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
J Cell Sci
TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.
Whole-genome DNA methylation and DNA methylation-based biomarkers in lung squamous cell carcinoma
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
Tripartite motif-containing 15 overexpression in non-small cell lung cancer is associated with poor patient prognoses.
Cell Death Dis
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs