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TRIM38 Polyclonal antibody, PBS Only (13405-1-PBS)

Filter: AllWBIHCIF/ICC

WB analysis of human liver using 13405-1-AP (same clone as 13405-1-PBS)
human liver tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
WB analysis of human colon using 13405-1-AP (same clone as 13405-1-PBS)
human colon tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
WB analysis of HEK-293 using 13405-1-AP (same clone as 13405-1-PBS)
HEK-293 cells were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)
Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)
Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.
IF Staining of L02 using 13405-1-AP (same clone as 13405-1-PBS)
Immunofluorescent analysis of (-20℃ Ethanol) fixed L02 cells using 13405-1-AP (TRIM38 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

Featured Product
KD/KO Validated

TRIM38 Polyclonal antibody, PBS Only

Name: TRIM38 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 13405-1-PBS

TRIM38 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 13405-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

13405-1-PBS targets TRIM38 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag3840 Product name: Recombinant human TRIM38 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 117-466 aa of BC026930 Sequence: RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD Predict reactive species
Full Name	tripartite motif-containing 38
Calculated Molecular Weight	465 aa, 53 kDa
Observed Molecular Weight	53 kDa
GenBank Accession Number	BC026930
Gene Symbol	TRIM38
Gene ID (NCBI)	10475
RRID	AB_2208307
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	O00635
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

The proinflammatory cytokines TNFα and IL-1β play central roles in many diseases, including infectious diseases, autoimmunity, and cancers. TRIM38 belongs to the TRIM protein family that is involved in various biological processes, including cell proliferation and apoptosis, innate immunity, and inflammatory response. It has been shown that TRIM38 acts as a suppressor in TOLL-like receptor (TLR)-mediated IFN-β induction by promoting degradation of TRAF6 and NAP1 through the ubiquitinproteasome system. (PMID:24434549)