TRMT10C Recombinant antibody, PBS Only

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  WB analysis using 84991-4-RR (same clone as 84991-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84991-4-RR (TRMT10C antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84991-4-PBS in a different storage buffer formulation.

TRMT10C Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84991-4-PBS

Clone No.242522B5

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Synonyms

RG9MTD1, 242522B5, MRPP1

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Product Information

84991-4-PBS targets TRMT10C in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: TRMT10C fusion protein Ag30642
• Full Name: RNA (guanine-9-) methyltransferase domain containing 1
• Calculated Molecular Weight: 47 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: NM_017819
• Gene Symbol: TRMT10C
• Gene ID (NCBI): 54931
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q7L0Y3
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

tRNA methyltransferase 10 homolog C (TRMT10C, also known as MRPP1) is involved in mitochondrial RNA processing and modification (PMID: 21593607). It is essential for the 5'-ends processing of mitochondrial tRNAs and plays a critical role in mitochondrial respiration and translation (PMID: 18984158; 29040705). Mutations in TRMT10C may be a cause of mitochondrial disease and highlight the importance of RNA processing for correct mitochondrial function (PMID: 27132592).