Product Information
55017-1-AP targets TSC22D4 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | TSC22 domain family, member 4 |
| Calculated Molecular Weight | 41 kDa |
| Observed Molecular Weight | 41-45 kDa |
| GenBank Accession Number | NM_030935 |
| Gene Symbol | TSC22D4 |
| Gene ID (NCBI) | 81628 |
| RRID | AB_10860903 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y3Q8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TSC22D4, also named as TILZ2 and THG-1, is a transcriptional repressor. It is a leucine zipper-containing protein that is highly conserved during evolution. TSC22D4 is transcriptionally up-regulated by many different stimuli, including anti-cancer drugs and growth inhibitors. It plays a suppressive role in tumorigenesis. TSC22D4 interacts with TSC22D1 by forming heterodimers(PMID:10488076).This antibody is specific to TSC22D4.
Publications
What published studies show
The TSC22D4 Polyclonal antibody (Cat# 55017-1-AP) has 1 total citation. It appears in the Journal of Cellular Physiology, in a 2019 study examining how TGF-β-stimulated TSC22 domain family proteins regulate cell-cycle dynamics in medulloblastoma cells. The associated research fields include cell cycle regulation, cancer biology (medulloblastoma), and TGF-β signaling pathways. The antibody was used for Western blot and immunoprecipitation in human samples.
| Species | Application | Title |
|---|---|---|
J Cell Physiol The interplay between TGF-β-stimulated TSC22 domain family proteins regulates cell-cycle dynamics in medulloblastoma cells
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