TSLP Polyclonal antibody

TSLP Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 13778-1-AP

Synonyms

thymic stromal lymphopoietin, TSLP



Tested Applications

Positive IHC detected inhuman kidney tissue, human testis tissue, human spleen tissue, human lung tissue, human ovary tissue, human prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13778-1-AP targets TSLP in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TSLP fusion protein Ag4771
Full Name thymic stromal lymphopoietin
Calculated Molecular Weight 15 kDa, 42 kDa
GenBank Accession NumberBC016720
Gene Symbol TSLP
Gene ID (NCBI) 85480
RRIDAB_2208528
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain, it mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Another isoform of this protein may act as an antimicrobial peptide in the oral cavity and on the skin (PMID: 24850429).

Protocols

Product Specific Protocols
IHC protocol for TSLP antibody 13778-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIHC

J Invest Dermatol

Retracing from Outcomes to Causes: NRF2-Driven GSTA4 Transcriptional Regulation Controls Chronic Inflammation and Oxidative Stress in Atopic Dermatitis Recurrence

Authors - Xin Ma
human,mouseIHC

Int Immunopharmacol

Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps

Authors - Meiping Zhang
humanIHC

Br J Dermatol

Elevations in Th2-initiating cytokines (IL-33, IL-25, TSLP) in lesional skin from Chronic Spontaneous ("Idiopathic") Urticaria.

Authors - A B Kay
humanIHC

J Immunol Res

Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells.

Authors - Si-Zhe Li

J Transl Med

TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease

Authors - Hui Lu
humanIHC

Mediators Inflamm

Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses

Authors - Si-Zhe Li

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Becky (Verified Customer) (07-30-2018)

It would be great to have this ab stable at 4C. I only use 1uL at a time for ELISA, and storage is -20.

  • Applications: Other (please state below),
  • Primary Antibody Dilution: 1ug/mL
  • Cell Tissue Type: recombinant human TSLP protein coated at 2ug/mL