TSPAN3 Polyclonal antibody, PBS Only

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• TSPAN3 Polyclonal antibody, PBS Only (13036-1-PBS)

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  IHC staining of mouse brain using 13036-1-AP (same clone as 13036-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13036-1-AP (TSPAN3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13036-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 13036-1-AP (same clone as 13036-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13036-1-AP (TSPAN3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13036-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 13036-1-AP (same clone as 13036-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TSPAN3 antibody (13036-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 13036-1-PBS in a different storage buffer formulation.

TSPAN3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 13036-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

Tspan-3, Transmembrane 4 superfamily member 8, TM4SF8, Tetraspanin-3, Tetraspanin TM4-A

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Product Information

13036-1-PBS targets TSPAN3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag3689

  Product name: Recombinant human TSPAN3 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-253 aa of BC011206

  Sequence: MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA

• Full Name: tetraspanin 3
• Calculated Molecular Weight: 253 aa, 28 kDa
• GenBank Accession Number: BC011206
• Gene Symbol: TSPAN3
• Gene ID (NCBI): 10099
• RRID: AB_3085406
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O60637
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Tetraspanin-3 (TSPAN3, also known as TM4SF8) is a member of the tetraspanin (TM4SF) family. Tetraspanins, so named because they contain four transmembrane domains, are frequently expressed at the cell surface in association with each other and with other molecules, and they function to regulate cell adhesion, migration, proliferation, and differentiation. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair. TSPAN3 is a glycosylated protein and it is differentially glycosylated in different tissues (PMID: 27818272).