TTC7B Polyclonal antibody, PBS Only

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• TTC7B Polyclonal antibody, PBS Only (25713-1-PBS)

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  WB analysis of mouse brain using 25713-1-AP (same clone as 25713-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 25713-1-AP (TTC7B antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 25713-1-AP (same clone as 25713-1-PBS)

  IP result of anti-TTC7B (IP:25713-1-AP, 4ug; Detection:25713-1-AP 1:600) with K-562 cells lysate 1640 ug. This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 25713-1-AP (same clone as 25713-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25713-1-AP (TTC7B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

TTC7B Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Cat No. 25713-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IP, Indirect ELISA

Synonyms

c14_5685, Tetratricopeptide repeat protein 7-like-1, TPR repeat protein 7 like 1, TPR repeat protein 7B, TPR repeat protein 7-like-1

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Product Information

25713-1-PBS targets TTC7B in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag22388

  Product name: Recombinant human TTC7B protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 96-318 aa of BC153122

  Sequence: LQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAGDIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPCQSPLDDPLRKGANTKTYTLTRRARVYSGENI

• Full Name: tetratricopeptide repeat domain 7B
• Calculated Molecular Weight: 843 aa, 94 kDa
• Observed Molecular Weight: 50-53 kDa
• GenBank Accession Number: BC153122
• Gene Symbol: TTC7B
• Gene ID (NCBI): 145567
• RRID: AB_2880205
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q86TV6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TTC7B (Tetratricopeptide Repeat Domain 7B) is a protein-coding gene belonging to the tetratricopeptide repeat (TPR) family, which plays critical roles in cellular signaling, membrane dynamics, and disease pathogenesis. TTC7B is associated with focal adhesion (FA) disassembly and cell migration, promoting tumor invasion and metastasis. Its expression is tied to FA-related pathways like the PINCH-ILK-PARVIN complex (PMID: 37990988).