TWIST1 Antibody
TWIST1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
WB, ELISA
Conjugate
Unconjugated
Publications
17
Cat no : 18125-1-AP
Synonyms
ACS3, bHLHa38, BPES2, BPES3, H twist, SCS, TWIST, twist homolog 1 (Drosophila), Twist related protein 1, TWIST1
Validation Data Gallery
Tested Applications
| Positive WB detected in | PC-3 cells, MCF-7 cells, SGC-7901 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| WB | See 16 publications below |
| IHC | See 2 publications below |
Product Information
The 18125-1-AP immunogen is Fusion Protein TWIST1 protein expressed in E. coli.
| Reactivity | human |
| Cited Species | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TWIST1 fusion protein Ag12700 |
| Full Name | twist homolog 1 (Drosophila) |
| Calculated molecular weight | 202aa,21 kDa |
| Observed molecular weight | 22, 28, 45-60 kDa |
| GenBank accession number | BC036704 |
| Gene symbol | TWIST1 |
| Gene ID (NCBI) | 7291 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20oC. Aliquoting is unnecessary for -20oC storage. |
Background Information
TWIST1, a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. It is also implicated in tumorigenesis, invasion and metastasis. TWIST1 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).
Publications
| Species | Application | Title |
|---|---|---|
J Cell Mol Med SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p. | ||
Int J Biochem Cell Biol Blue light emitting diodes irradiation causes cell death in colorectal cancer by inducing ROS production and DNA damage. | ||
Acta Biochim Biophys Sin (Shanghai) STK33 plays an important positive role in the development of human large cell lung cancers with variable metastatic potential. | ||
Biomed Pharmacother Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats. | ||
Biomed Pharmacother Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro. |
