Tested Applications
| Positive WB detected in | HEK-293 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
12927-1-AP targets TXNL4B in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3620 Product name: Recombinant human TXNL4B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-149 aa of BC009646 Sequence: MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI Predict reactive species |
| Full Name | thioredoxin-like 4B |
| Calculated Molecular Weight | 149 aa, 17 kDa |
| Observed Molecular Weight | 17 kDa |
| GenBank Accession Number | BC009646 |
| Gene Symbol | TXNL4B |
| Gene ID (NCBI) | 54957 |
| RRID | AB_2877893 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NX01 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TXNL4B(Thioredoxin-like protein 4B) is also named as DIM2, DLP and belongs to the DIM1 family. It is implicated in not only cell cycle progression but also in a more specific molecular process such as pre-mRNA splicing. It is required for S/G(2) transition.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TXNL4B antibody 12927-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The TXNL4B Polyclonal antibody (Cat# 12927-1-AP) has 1 citation. It appears in MedComm (Impact Factor 14.1), published in 2023. The study investigated how TXNL4B regulates radioresistance by controlling PRP3-mediated alternative splicing of FANCI, placing it in the research fields of RNA splicing, radiation biology, and Fanconi anemia pathway. The antibody was validated in human samples for WB, IHC, and IF applications.
| Species | Application | Title |
|---|---|---|
MedComm (2020) TXNL4B regulates radioresistance by controlling the PRP3-mediated alternative splicing of FANCI
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