Product Information
31971-1-PBS targets Teneurin-3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36331 Product name: Recombinant human ODZ3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 2388-2540 aa of NM_001080477 Sequence: RNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELVKSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSWLWFATVKSLIGKGVMLAVSQGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFT Predict reactive species |
| Full Name | odz, odd Oz/ten-m homolog 3 (Drosophila) |
| Calculated Molecular Weight | 300kDa |
| Observed Molecular Weight | 250 kDa |
| GenBank Accession Number | NM_001080477 |
| Gene Symbol | ODZ3 |
| Gene ID (NCBI) | 55714 |
| RRID | AB_3670162 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9P273 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Teneurin-3, also known as Ten-m3, Odz3, Ten-m/Odz3, is a ~300 kDa type II transmembrane glycoprotein that is a member of the teneurin/Ten-m/Odz family. Ten-m3 plays a critical role in regulating connectivity of the nervous system, particularly in axon pathfinding and synaptic organisation in the motor and visual system. Mutation in the TENM3/ODZ3 gene in humans has been associated with the eye condition, microphthalmia (PMID 22766609). TENM3 is expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined.
