|Positive WB detected in||human placenta tissue|
|Positive IHC detected in||human stomach tissue, mouse stomach tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:200-1:800|
|Sample-dependent, check data in validation data gallery|
10858-1-AP targets Timp-3 in WB, IHC,ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Timp-3 fusion protein Ag1253|
|Full Name||TIMP metallopeptidase inhibitor 3|
|Calculated molecular weight||24 kDa|
|Observed molecular weight||21-24 kDa|
|GenBank accession number||BC014277|
|Gene ID (NCBI)||7078|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Onco Targets Ther
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
J Toxicol Pathol
Databases for technical aspects of immunohistochemistry.
EZH2 regulates cancer cell migration through repressing TIMP-3 in non-small cell lung cancer.
Mol Cell Biochem
Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries.
Cardiovasc Diagn Ther
MicroRNA-221 promotes proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) by targeting tissue inhibitor of metalloproteinases-3 (TIMP3).
Lack of Correlation between Aberrant p16, RAR-β2, TIMP3, ERCC1, and BRCA1 Protein Expression and Promoter Methylation in Squamous Cell Carcinoma Accompanying Candida albicans-Induced Inflammation.