UBASH3A-Specific Polyclonal antibody, PBS Only

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• UBASH3A-Specific Polyclonal antibody, PBS Only (15823-1-PBS)

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  WB analysis using 15823-1-AP (same clone as 15823-1-PBS)

  mouse bone marrow tissue were subjected to SDS PAGE followed by western blot with 15823-1-AP (UBASH3A-Specific antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15823-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse spleen using 15823-1-AP (same clone as 15823-1-PBS)

  IP result of anti-UBASH3A-Specific (IP:15823-1-AP, 4ug; Detection:15823-1-AP 1:500) with mouse spleen tissue lysate 1920 ug. This data was developed using the same antibody clone with 15823-1-PBS in a different storage buffer formulation.

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  IF Staining of THP-1 using 15823-1-AP (same clone as 15823-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using UBASH3A-Specific antibody (15823-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 15823-1-PBS in a different storage buffer formulation.

UBASH3A-Specific Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA

Cat No. 15823-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, IP, Indirect ELISA

Synonyms

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Product Information

15823-1-PBS targets UBASH3A-Specific in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: ubiquitin associated and SH3 domain containing, A
• Calculated Molecular Weight: 74 kDa
• Observed Molecular Weight: 70-74 kDa
• GenBank Accession Number: NM_018961
• Gene Symbol: UBASH3A
• Gene ID (NCBI): 53347
• RRID: AB_2272584
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P57075
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A (UBASH3A) also known as T-cell ubiquitin ligand 1 (TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor (AIF). This antibody is UBASH3A-specific.