UGT1A6 Polyclonal antibody

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  WB analysis using 23765-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 23765-1-AP (UGT1A6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 23765-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 23765-1-AP (UGT1A6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

UGT1A6 Polyclonal Antibody for WB, ELISA

Cat No. 23765-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

UDP-glucuronosyltransferase 1-6, Phenol-metabolizing UDP-glucuronosyltransferase, HLUGP1, HLUGP, GNT1

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Tested Applications

• Positive WB detected in: NCI-H1299 cells, mouse liver tissue, rat liver tissue, mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

23765-1-AP targets UGT1A6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag20635

  Product name: Recombinant human UGT1A6 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 176-488 aa of BC019861

  Sequence: CSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMATADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSL

• Full Name: UDP glucuronosyltransferase 1 family, polypeptide A6
• Calculated Molecular Weight: 532 aa, 61 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC019861
• Gene Symbol: UGT1A6
• Gene ID (NCBI): 54578
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P19224
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UDP-glucuronosyltransferase 1-6 (UGT1A6, also known as GNT1 and UGT1) plays a crucial role in the glucuronidation of numerous drugs, toxins, and endogenous substrates. This process is essential for detoxifying and excreting lipophilic compounds, primarily in the liver (PMID: 15761114).

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
		Clin Transl Oncol; UGT1A6 in pancreatic cancer: a promising prognostic biomarker and therapeutic target; Authors - Xue-An Lu