UNC13B Polyclonal antibody

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  WB analysis using 21839-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 21839-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

UNC13B Polyclonal Antibody for WB, ELISA

Cat No. 21839-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

unc-13 homolog B , Protein unc-13 homolog B, Munc13-2

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Tested Applications

• Positive WB detected in: HEK-293 cells, mouse brain tissue, HeLa cells, SH-SY5Y cells, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

21839-1-AP targets UNC13B in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: UNC13B fusion protein Ag16478
• Full Name: unc-13 homolog B (C. elegans)
• Calculated Molecular Weight: 1610 aa, 183 kDa
• Observed Molecular Weight: 180 kDa
• GenBank Accession Number: BC111781
• Gene Symbol: UNC13B
• Gene ID (NCBI): 10497
• RRID: AB_3669376
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O14795
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UNC13A is a member of the unliganded-13 (UNC13) family and plays a crucial role in synaptic vesicle priming and exocytosis. UNC13B has been implicated in autism spectrum disorder (ASD), partial epilepsy, and schizophrenia (PMID: 38188011).