UNC5A-Specific Recombinant monoclonal antibody, PBS Only

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  WB analysis using 86582-1-RR (same clone as 86582-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86582-1-RR (UNC5A-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86582-1-PBS in a different storage buffer formulation.

UNC5A-Specific Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86582-1-PBS

Clone No.251526D11

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

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Product Information

86582-1-PBS targets UNC5A-Specific in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: unc-5 homolog A (C. elegans)
• Calculated Molecular Weight: 93 kDa
• Observed Molecular Weight: 103 kDa
• GenBank Accession Number: NM_133369
• Gene Symbol: UNC5A
• Gene ID (NCBI): 90249
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q6ZN44
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.