Product Information
20238-1-AP targets UNC5B-Specific in ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | unc-5 homolog B (C. elegans) |
| Calculated Molecular Weight | 104 kDa |
| GenBank Accession Number | NM_170744 |
| Gene Symbol | UNC5B |
| Gene ID (NCBI) | 219699 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IZJ1 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
UNC5B, also named as P53RDL1 and UNC5H2, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. UNC5B mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. This antibody is specific to UNC5B.
