UPF3B Recombinant antibody, PBS Only

• 

  WB analysis using 86035-1-RR (same clone as 86035-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86035-1-RR (UPF3B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86035-1-PBS in a different storage buffer formulation.

UPF3B Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 86035-1-PBS

Clone No.250604F11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

RENT3B, hUpf3B, hUpf3p X, hUpf3p-X, MRXS14

---

Product Information

86035-1-PBS targets UPF3B in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: UPF3B fusion protein Ag18568
• Full Name: UPF3 regulator of nonsense transcripts homolog B (yeast)
• Calculated Molecular Weight: 483 aa, 58 kDa
• Observed Molecular Weight: 58 kDa
• GenBank Accession Number: BC121017
• Gene Symbol: UPF3B
• Gene ID (NCBI): 65109
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9BZI7
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Regulator of nonsense transcripts 3B (UPF3B) is also named as RENT3B, and belongs to the RENT3 family. UPF3B is a core junction protein in the Nonsense-mediated RNA decay (NMD) pathway, involved in the exonuclear transport and quality supervision of mRNA. And UPF3B showed heightened expression in hepatocellular carcinoma (HCC) tissues and was linked with adverse prognosis (PMID: 38889220). UPF3B promotes the dissociation of post-termination ribosomal complexes that lack nascent peptide. UPF3B could promote ribosome recycling, and UPF3B serves as a direct regulator of translation termination (PMID: 29333258).