UPK2-Specific Polyclonal antibody

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  IHC staining of human bladder using 19733-1-AP

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human bladder using 19733-1-AP

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human bladder using 19733-1-AP

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human bladder using 19733-1-AP

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:50 (under 40x lens).

UPK2-Specific Polyclonal Antibody for IHC, ELISA

Cat No. 19733-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Synonyms

UP2, UPII, upk 2, UPK2, UPK2-Specific, uroplakin 2, Uroplakin II

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Tested Applications

• Positive IHC detected in: human bladder tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

19733-1-AP targets UPK2-Specific in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: uroplakin 2
• Calculated Molecular Weight: 19 kDa
• GenBank Accession Number: NM_006760
• Gene Symbol: UPK2
• Gene ID (NCBI): 7379
• RRID: AB_2878602
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O00526
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-2 (UPK2) is a single-pass type I membrane protein. UPK2 may play an important role in regulating the assembly of the AUM.