UTP23 Polyclonal antibody

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  WB analysis of mouse liver using 15950-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse liver using 15950-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

UTP23 Polyclonal Antibody for WB, ELISA

Cat No. 15950-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

rRNA-processing protein UTP23 homolog, C8orf53

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Tested Applications

• Positive WB detected in: mouse liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 1 publications below

Product Information

15950-1-AP targets UTP23 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: UTP23 fusion protein Ag8609
• Full Name: UTP23, small subunit (SSU) processome component, homolog (yeast)
• Calculated Molecular Weight: 249 aa, 28 kDa
• Observed Molecular Weight: 28 kDa, 17 kDa
• GenBank Accession Number: BC005955
• Gene Symbol: UTP23
• Gene ID (NCBI): 84294
• RRID: AB_10644292
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9BRU9
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UTP23 is a component of ribosomal small-subunit processome, which is involved in ribosome synthesis and RNA maturation. UTP23 contains a long and likely unstructured tail at the C terminus of the PIN domain (PMID: 24152547). UTP23 is a target of genetic variation associated with colorectal cancer in chromosome 8q23.3, and it may coordinate with EIF3H in this region in the development of colorectal cancer. Low expression of UTP23 predicts poorer prognosis of ovarian cancer patients (PMID: 31540773, 37880005). It has 2 predicted molecular weight of 28 kDa and 17 kDa.

Publications

Species	Application	Title
human	WB,IHC	Clin Breast Cancer; UTP23 Functions in Breast Cancer Progression and Predicts Poor Prognosis of Luminal a Breast Cancer; Authors - Sida Zhang