Uteroglobin/CC10 Antibody

Uteroglobin/CC10 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat, mouse

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 26909-1-AP

Synonyms

CC10, CC16, CCPBP, CCSP, SCGB1A1, UGB, UP 1, UP1, Urinary protein 1, Urine protein 1, Uteroglobin



Tested Applications

Positive WB detected inrat lung tissue
Positive IHC detected inhuman lung tissue, mouse lung tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inA549 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Published Applications

IHCSee 1 publications below

Product Information

The 26909-1-AP immunogen is Fusion Protein Uteroglobin/CC10 protein expressed in E. coli.

Tested Reactivity human, rat, mouse
Cited Reactivity rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Uteroglobin/CC10 fusion protein Ag25530
Full Name secretoglobin, family 1A, member 1 (uteroglobin)
Calculated molecular weight 10 kDa
Observed molecular weight 9 kDa
GenBank accession number BC004481
Gene symbol SCGB1A1
Gene ID (NCBI) 7356
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Protocols

Product Specific Protocols
WB protocol for Uteroglobin/CC10 antibody 26909-1-APDownload protocol
IHC protocol for Uteroglobin/CC10 antibody 26909-1-APDownload protocol
IF protocol for Uteroglobin/CC10 antibody 26909-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratIHC

Front Pediatr

Impaired FGF10 Signaling and Epithelial Development in Experimental Lung Hypoplasia With Esophageal Atresia.

Authors - Jun Wang