VDAC3 Polyclonal antibody

VDAC3 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 14451-1-AP

Synonyms

HD VDAC3, hVDAC3, VDAC 3, VDAC3



Tested Applications

Positive WB detected inmouse heart tissue, human brain tissue, human heart tissue, mouse brain tissue
Positive IHC detected inhuman liver cancer tissue, human osteosarcoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14451-1-AP targets VDAC3 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen VDAC3 fusion protein Ag5960
Full Name voltage-dependent anion channel 3
Calculated molecular weight 31 kDa
Observed molecular weight 30 kDa
GenBank accession numberBC056870
Gene symbol VDAC3
Gene ID (NCBI) 7419
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

VDAC3 belongs to the eukaryotic mitochondrial porin family. It forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.

Protocols

Product Specific Protocols
WB protocol for VDAC3 antibody 14451-1-APDownload protocol
IHC protocol for VDAC3 antibody 14451-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cancer Res

miR-450a acts as a tumor suppressor in ovarian cancer by regulating energy metabolism.

Authors - Bruna Rodrigues Muys
humanWB

Front Aging Neurosci

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis.

Authors - Yue-Qi Wang
WB

J Cell Sci

Doublet 7 shortening, doublet 5-preferential poly-Glu reduction, and beating stall of sperm flagella in Ttll9-/- mice.

Authors - Alu Konno
humanIHC

Oncotarget

Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.

Authors - Changlin Zhang
mouseWB

Mol Ther Nucleic Acids

Salvia miltiorrhiza-Derived Sal-miR-58 Induces Autophagy and Attenuates Inflammation in Vascular Smooth Muscle Cells.

Authors - Yan Qin
humanWB

Cell Res

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Authors - Pengli Zheng