VLDLR Polyclonal antibody

VLDLR Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 19493-1-AP

Synonyms

CHRMQ1, VLDL R, VLDL receptor, VLDLR, VLDLRCH



Tested Applications

Positive WB detected inMCF-7 cells, mouse ovary tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 3 publications below

Product Information

19493-1-AP targets VLDLR in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse, rat, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name very low density lipoprotein receptor
Calculated molecular weight 96 kDa
Observed molecular weight 96 kDa, 160 kDa
GenBank accession numberNM_003383
Gene symbol VLDLR
Gene ID (NCBI) 7436
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.

Protocols

Product Specific Protocols
WB protocol for VLDLR antibody 19493-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

PLoS One

Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.

Authors - Limin Liu
ratWB

Front Pharmacol

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats.

Authors - Xue Wu
zebrafishWB

Neuron

Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.

Authors - Hilliard Austin T AT