Product Information
14766-1-AP targets WDR4 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | WDR4 fusion protein Ag6531 Predict reactive species |
| Full Name | WD repeat domain 4 |
| Calculated Molecular Weight | 30 kDa |
| Observed Molecular Weight | 30 kDa |
| GenBank Accession Number | BC001074 |
| Gene Symbol | WDR4 |
| Gene ID (NCBI) | 10785 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P57081 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
A group of functionally diverse regulatory proteins in eukaryotes, defined by a conserved core of 4 or more modular repeat units, is known as the WD repeat family. Proteins belonging to the WD repeat family are involved in a number of cellular processes, including cell cycle progression, apoptosis, signal transduction, and gene regulation. WD repeat-containing protein 4 (WDR4) belongs to the WD repeat family, and is required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. It acts to stablize and induce conformation change of the catalytic subunit in the complex. There exists three isoforms, while isoform1, 2 are 45kDa band, and isoform 3 is 30 kDa band.
