XPO7 Polyclonal antibody

• Featured Product
• KD/KO Validated

XPO7 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

3

Cat no : 12980-1-AP

Synonyms

Exp7, exportin 7, KIAA0745, Ran binding protein 16, RANBP16, XPO7

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Validation Data Gallery

• 

  WB analysis of K-562 using 12980-1-AP

  K-562 cells were subjected to SDS PAGE followed by western blot with 12980-1-AP (XPO7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 12980-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 12980-1-AP (XPO7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse spleen using 12980-1-AP

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 12980-1-AP (XPO7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human brain using 12980-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 12980-1-AP (XPO7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse brain tissue, mouse spleen tissue, K-562 cells, human brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IF: See 1 publications below

Product Information

12980-1-AP targets XPO7 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: XPO7 fusion protein Ag3603
• Full Name: exportin 7
• Calculated Molecular Weight: 1087 aa, 124 kDa
• Observed Molecular Weight: 100-110 kDa
• GenBank Accession Number: BC030785
• Gene Symbol: XPO7
• Gene ID (NCBI): 23039
• RRID: AB_2215493
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
human	WB,IF	Sci Rep; TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia.; Authors - Hilary C Archbold ; KD Validated
human	WB	Front Immunol; A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx.; Authors - Christine D Landsberg
human	WB	Neuron; Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes; Authors - Norah Al-Azzam