ZFYVE26 Recombinant monoclonal antibody, PBS Only

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  IHC staining of mouse heart using 83215-4-RR (same clone as 83215-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 83215-4-RR (ZFYVE26 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83215-4-PBS in a different storage buffer formulation.

ZFYVE26 Uni-rAb^® Recombinant Antibody for IHC, ELISA

Cat No. 83215-4-PBS

Clone No.230493D3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Synonyms

SPG15, Spastizin, KIAA0321, 230493D3

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Product Information

83215-4-PBS targets ZFYVE26 in IHC, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: zinc finger, FYVE domain containing 26
• Calculated Molecular Weight: 285 kDa
• GenBank Accession Number: NM_015346
• Gene Symbol: ZFYVE26
• Gene ID (NCBI): 23503
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q68DK2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ZFYVE26 is a large protein of 2539 amino acid residues and contains an FYVE domain that confers to the protein binding affinity to the membrane-associated phosphatidylinositol 3-phosphate (PtdIns3P). ZFYVE26 has a diffuse cytoplasmic distribution and partially colocalizes with early endosomes, the endoplasmic reticulum, microtubules, and vesicles. It also localizes to the midbody during cytokinesis (PMID: 24284334).