ZIC1 Polyclonal antibody, PBS Only

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• ZIC1 Polyclonal antibody, PBS Only (25004-1-PBS)

• 

  WB analysis using 25004-1-AP (same clone as 25004-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25004-1-PBS in a different storage buffer formulation.

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  WB analysis of Y79 using 25004-1-AP (same clone as 25004-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25004-1-PBS in a different storage buffer formulation.

ZIC1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 25004-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

25004-1-PBS targets ZIC1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag13400

  Product name: Recombinant human ZIC1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 99-447 aa of BC104848

  Sequence: DFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEWYV

• Full Name: Zic family member 1 (odd-paired homolog, Drosophila)
• Calculated Molecular Weight: 447 aa, 48 kDa
• Observed Molecular Weight: ~50 kDa
• GenBank Accession Number: BC104848
• Gene Symbol: ZIC1
• Gene ID (NCBI): 7545
• RRID: AB_3085766
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q15915
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family. In vertebrates, the ZIC gene family plays an important role in neural crest and subsequent cerebellar development. Mutations in ZIC family members have demonstrated that they are essential for proper development of the neural tube, left-right symmetry, and muscle and skeletal development. It has been reported that ZIC1 participates in the regulation of cell proliferation in the dorsal neural tube by inhibition of neural differentiation. Furthermore, ZIC1 is potentially involved in the oncogenesis of undifferentiated nervous system tumors. (PMID:17936758)