ZNF800 Polyclonal antibody

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• ZNF800 Polyclonal antibody (33930-1-AP)

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  WB analysis using 33930-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33930-1-AP (ZNF800 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

ZNF800 Polyclonal Antibody for WB, ELISA

Cat No. 33930-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

PP902, Zinc finger protein 800

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Tested Applications

• Positive WB detected in: K-562 cells, MCF-7 cells, MDA-MB-231 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

33930-1-AP targets ZNF800 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag40831

  Product name: Recombinant human ZNF800 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 91-220 aa of BC110624

  Sequence: YCPPSLQMDDNLPDVNDKQSQAINDLLEAIYPSVDKREYIIKLEPIETNQNAVFQYISRTDNPIEVTESSSTPEQTEVQIQETSTEQSKTVPVTDTEVETVEPPPVEIVTDEVAPTSDEQPQESQADLET

• Full Name: zinc finger protein 800
• Calculated Molecular Weight: 664 aa, 75 kDa
• Observed Molecular Weight: 80 kDa
• GenBank Accession Number: BC110624
• Gene Symbol: ZNF800
• Gene ID (NCBI): 168850
• RRID: AB_3743115
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q2TB10
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ZNF800 (Zinc Finger Protein 800) is a DNA-binding transcription factor containing a C2H2-type zinc finger domain. It is localized in the nucleus and participates in the regulation of gene expression. This protein plays a critical inhibitory role in the differentiation of enteroendocrine cells (EECs). By directly binding to the promoter regions of transcription factors such as PAX4, SOX4, and INSM1, it blocks the EEC differentiation program and maintains intestinal epithelial homeostasis. In cancer research, ZNF800 is highly expressed in various malignant tumors, including low-grade glioma and lung cancer, where it promotes tumor cell proliferation, migration, and invasion. Its expression level is significantly correlated with shortened overall survival of patients, serving as an independent prognostic predictor. Furthermore, ZNF800 expression is positively correlated with immune cell infiltration in the tumor microenvironment and the expression of immune checkpoint molecules such as PD-1/PD-L1, suggesting its potential role in tumor immune evasion.