NeutraKine® Beta NGF Monoclonal antibody

NeutraKine® Beta NGF Monoclonal Antibody for Neutralization,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Neutralization,ELISA

Conjugate

Unconjugated

CloneNo.

4F9H1

Cat no : 69009-1-Ig

Synonyms

Beta nerve growth factor, Beta NGF, HSAN5, NGF, NGFB, proNGF



Tested Applications

NeutralizationMeasured by its ability to neutralize Human beta-NGF induced proliferation of TF-1 cell line (human erythroleukemic cell line) . The half neutralization dose (ND50) is typically 4-20 ng/mL in the presence of 2 ng/mL human beta-NGF.

Product Information

69009-1-Ig targets NeutraKine® Beta NGF in Neutralization,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human NeutraKine® Beta NGF protein HZ-1222
Full Name nerve growth factor (beta polypeptide)
Gene symbol NGF
Gene ID (NCBI) 4803
Conjugate Unconjugated
Form Lyophilized Powder
Purification Method Protein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Beta nerve growth factor (NGF) is critical for the survival and maintenance of sympathetic and sensory neurons and may play an important role in the regulation of the immune system (PMID 16842161). The presence of beta NGF in immune cells, endocrine cells, and the CNS limbic areas suggests that beta NGF may function as an intracellular messenger to regulate the body's response to stress (PMID 19442684).

This antibody is used to Block/Neutralize Beta nerve growth factor protein.

Protocols

Product Specific Protocols
Neutralization protocol of NeutraKine® Beta NGF antibody 69009-1-IgDownload protocol
Standard Protocols
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