c-SRC Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 25978-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
A431 cells, CHO cells, COLO 320 cells, Jurkat cells, mouse brain tissue

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Calculated molecular weight:
60 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SRC

Synonyms
ASV, c SRC, c-SRC, p60 Src, pp60c src, Proto oncogene c Src, SRC, SRC1
Background

SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.


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