fibrosin Polyclonal antibody, PBS Only

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• fibrosin Polyclonal antibody, PBS Only (11356-1-PBS)

• 

  WB analysis of mouse kidney using 11356-1-AP (same clone as 11356-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11356-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 11356-1-AP (same clone as 11356-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11356-1-PBS in a different storage buffer formulation.

fibrosin Polyclonal Antibody for Indirect ELISA

Cat No. 11356-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

Indirect ELISA

Synonyms

FBRS, Probable fibrosin-1, FBSH, FBS1, FBS

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Product Information

11356-1-PBS targets fibrosin in Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag1870

  Product name: Recombinant human FBRS protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-344 aa of BC014212

  Sequence: MHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLPALMKPQ

• Full Name: fibrosin
• Calculated Molecular Weight: 52 kDa
• Observed Molecular Weight: 48-52 kDa
• GenBank Accession Number: BC014212
• Gene Symbol: fibrosin
• Gene ID (NCBI): 64319
• RRID: AB_10697650
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9HAH7
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation FBRS (or FBS1) gene, encoding fibrosin (or fibrosin-1), was first cloned by Prakash et al. and was found to be able to stimulate several biological activities related to scarring as a fibrogenic lymphokine. Fibrosin is secreted by activated lymphocytes that induce fibroblast proliferation. In vitro application of fibrosin stimulates expression of alpha smooth muscle actin fibers and plays an important role in up regulating the appearance of myofibroblasts during wound healing and possibly in fibrotic diseases. Fibrosin is also implicated in alcohol-induced hepatic fibrosis in vivo.