p38 MAPK Polyclonal antibody

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• p38 MAPK Polyclonal antibody (51115-1-AP)

p38 MAPK Polyclonal Antibody for WB, ELISA

Cat No. 51115-1-AP Copied!

Publications (50)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, IF, ELISA

Synonyms

CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A

• 

  WB analysis using 51115-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51115-1-AP (p38 MAPK antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis using 51115-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51115-1-AP (p38 MAPK antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: mouse ovary tissue, NIH/3T3 cells, PC-12 cells, RAW 264.7 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

51115-1-AP targets p38 MAPK in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse, rat, pig
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: mitogen-activated protein kinase 14
• Calculated Molecular Weight: 360 aa, 41 kDa
• Observed Molecular Weight: 38 kDa
• GenBank Accession Number: BC031574
• Gene Symbol: p38 MAPK
• Gene ID (NCBI): 1432
• RRID: AB_3086430
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q16539
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing. This antibody is specific to MAPK14.

Publications

What published studies show

The p38 MAPK Polyclonal antibody (catalog number 51115-1-AP) has 50 citations. These appear in journals such as Advanced Science, Phytomedicine, International Journal of Biological Macromolecules, Molecular Medicine, Phytotherapy Research, Biomedical Pharmacotherapy, Journal of Ethnopharmacology, International Immunopharmacology, International Journal of Molecular Sciences, Scientific Reports, FASEB Journal, and Viruses Journal. Research fields span oncology, inflammation, osteoarthritis, cardiovascular disease, neurology, immunology, metabolism, and traditional medicine, with most studies using Western blot.

Automatically generated from the 50 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
mouse	WB	Adv Sci (Weinh); Ultra-Long-Term Anti-Inflammatory Polyphenol Capsule to Remodel the Microenvironment for Accelerating Osteoarthritis Healing by Single Dosage; Authors - Shaoyin Wei
		Phytomedicine; Sappanone A alleviates metabolic dysfunction-associated steatohepatitis by decreasing hepatocyte lipotoxicity via targeting Mup3 in mice; Authors - An Zhu
mouse	WB	Phytomedicine; Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway; Authors - Lei Zhao
	WB	Int J Biol Macromol; 5-HTR1D and 5-HTR2B regulated Cryptocaryon irritans-induced inflammatory response of large yellow croaker Larimichthys crocea; Authors - Xu Zhou
mouse	WB	Mol Med; Inhibition of CC chemokine receptor 1 ameliorates osteoarthritis in mouse by activating PPAR-γ; Authors - Hanqing Xu
mouse	WB	Phytother Res; Germacrone alleviates breast cancer-associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF-κB signaling pathways; Authors - Zhengjun Lin