• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human FLT3 Ligand protein

Activity

0.4-3.0 ng/mL EC50

Species Reactivity

human,mouse

Purity

>95%

Cat no : HZ-1151

Synonyms

FL, Flt3 ligand, Flt3L, FLT3LG, SL cytokine



Technical Specifications

GeneID 2323
Species Human
Expression HEK293
Activity 0.4-3.0 ng/mL EC50
Purity >95%
Endotoxin<1 EU/µg
Accession NumberP49771
Molecular Mass 24 to 30 kDa, monomer, glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human,mouse

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA)

Background

FMS-related tyrosine kinase 3 ligand (FLT3 Ligand) is a growth factor that regulates proliferation of early hematopoietic cells. FLT3 Ligand binds to cells expressing the tyrosine kinase receptor FLT3. FLT3 Ligand by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation (PMID: 8590775; 7544638; 12176867).

Synonyms

FL, Flt3 ligand, Flt3L, FLT3LG, SL cytokine

Publications

SpeciesTitle
human

Cell Res

Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions.

Authors - Min Tang
human

Blood

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo.

Authors - Y TerryLee
human

J Exp Med

Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.

Authors - AndrewVolk
human

Stem Cells

Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.

Authors - Niels-BjarneWoods
human

Hum Mol Genet

Modeling neuro-immune interactions during Zika virus infection.

Authors - Pinar Mesci
human

J Tissue Eng Regen Med

Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium.

Authors - ColleenByrnes