|Activity||0.4-3.0 ng/mL EC50|
|Molecular Mass||24 to 30 kDa, monomer, glycosylated|
|Formulation||1x PBS, See Certificate of Analysis for details|
Stability and Reconstitution
|Stability and Storage||Product Form||Temperature Conditions||Storage Time|
(From Date of Receipt)
|Lyophilized||-20°C to -80°C||Until Expiry Date|
|Lyophilized||Room Temperature||2 weeks|
|Reconstituted as per CofA||-20°C to -80°C||6 months|
|Reconstituted as per CofA||4°C||1 week|
|Avoid repeated freeze-thaw cycles.|
|Reconstitution||Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA)|
FMS-related tyrosine kinase 3 ligand (FLT3 Ligand) is a growth factor that regulates proliferation of early hematopoietic cells. FLT3 Ligand binds to cells expressing the tyrosine kinase receptor FLT3. FLT3 Ligand by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation (PMID: 8590775; 7544638; 12176867).
FL, Flt3 ligand, Flt3L, FLT3LG, SL cytokine
CD123 expression patterns and selective targeting with a CD123-specific antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia.
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