• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human LEFTY-1 protein

Activity

Typically ≤ 2.5 µg/mL EC50

Species Reactivity

human,mouse

Purity

>95%

Cat no : HZ-1109

Synonyms

LEFTB, LEFTY1, LEFTYB, Protein lefty 1, Protein lefty B



Technical Specifications

GeneID 10637
Species Human
Expression HEK293
Activity Typically ≤ 2.5 µg/mL EC50
Purity >95%
Endotoxin<1 EU/μg
Accession NumberO75610
Molecular Mass 38 kDa, monomer, glycosylated
Formulation 10 mM Tris-HCl pH 7.4 + 50 mM NaCl + 0.5% CHAPS, See Certificate of Analysis for details
Species Reactivity human,mouse

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Background

LEFTY-1 is a member of the TGF-beta family of proteins that plays a role in left-right asymmetry determination of organ systems during development. LEFTY-1 regulates transforming growth factor, mitogen-activated protein kinase and other signaling pathways, and is considered to have a potential anti-inflammatory function (PMID: 29286065; 26316705; 10500184; 9708731)

Synonyms

LEFTB, LEFTY1, LEFTYB, Protein lefty 1, Protein lefty B

Publications

SpeciesTitle
human

Stem Cells Dev

Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation.

Authors - ZhilaKhalkhali-Ellis