ADAMDEC1 Polyclonal antibody

ADAMDEC1 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 17899-1-AP

Synonyms

ADAM DEC1, ADAM like protein decysin 1, ADAM like, decysin 1, ADAMDEC1, M12.219



Tested Applications

Positive WB detected inMCF-7 cells
Positive IHC detected inhuman tonsillitis tissue, human lymphoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17899-1-AP targets ADAMDEC1 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADAMDEC1 fusion protein Ag12265
Full Name ADAM-like, decysin 1
Calculated Molecular Weight 470 aa, 53 kDa
Observed Molecular Weight 44 kDa
GenBank Accession NumberBC074877
Gene Symbol ADAMDEC1
Gene ID (NCBI) 27299
RRIDAB_2878461
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) was first identified as a unique member of the matrix metalloprotease (ADAM) family. ADAMs are increasingly recognized as playing an important role in gut homeostasis and bowel inflammation. ADAMDEC1 is abundantly, and almost exclusively, expressed in the gastrointestinal (GI) tract.

Protocols

Product Specific Protocols
WB protocol for ADAMDEC1 antibody 17899-1-APDownload protocol
IHC protocol for ADAMDEC1 antibody 17899-1-APDownload protocol
IF protocol for ADAMDEC1 antibody 17899-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

J Inflamm Res

The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome

Authors - Haishi Zheng
human,mouseWB,IHC

Thorac Cancer

Upregulation of ADAMDEC1 correlates with tumor progression and predicts poor prognosis in non-small cell lung cancer (NSCLC) via the PI3K/AKT pathway.

Authors - Weiliang Zhu
humanIHC

Aging (Albany NY)

An immune signature to predict the prognosis of ATRX-wildtype glioma patients and guide immune checkpoint blockade therapy

Authors - Wenpeng Cao
humanWB,IHC

Exp Cell Res

ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK3β

Authors - Yuna Jia
  • KD Validated
mouseWB

Funct Integr Genomics

Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression

Authors - Xiaochen Wang