AGR2 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 12275-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse stomach tissue, human colon tissue, human stomach tissue, mouse small intestine tissue, rat colon tissue, rat stomach tissue, SW 1990 cells

Positive IP detected in:
SW 1990 cells

Positive IHC detected in:
human breast cancer tissue, human colon tissue

Positive IF detected in:
MCF-7 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
anterior gradient homolog 2 (Xenopus laevis)

Calculated molecular weight:
175aa,20 kDa

Observed molecular weight:
17-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AGR2

Synonyms
AG 2, AG2, AGR2, GOB 4, HAG 2, HPC8, PDIA17, XAG 2
Background

AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.


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