GABARAPL1-Specific Antibody 21 Publications

Rabbit Polyclonal| Catalog number: 11010-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse, rat, monkey

Positive WB detected in:
rat brain tissue, HepG2 cells, human heart tissue, mouse liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human ovary tumor tissue, human liver tissue

Positive IF detected in:
Chloroquine treated HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GABA(A) receptor-associated protein like 1

Calculated molecular weight:
14 kDa

Observed molecular weight:
16 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GABARAPL1

Synonyms
APG8 LIKE, APG8L, ATG8, ATG8L, GABARAPL1, GEC 1, GEC1
Background

GABARAPL1 (GABARAP-like protein 1), also named as ATG8, GEC1, APG8L, ATG8L and APG8-LIKE, is a member of GABARP (GABAA receptor-associated protein) family. GABARAPL1 was initially identified as estrogen-regulated gene and the protein acts in receptor and vesicle transport. It’s also involved in the process of autophagy like GABARAP and GABARAPL2, and may be considered as an autophagic marker. It is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle and at very low levels in thymus and small intestine.The antibody is specific to GABARAPL1, and it doesn’t recognize the recombinant GABARAP and GABARAPL2.


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