ATM Monoclonal antibody

ATM Monoclonal Antibody for IF, WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

CloneNo.

3E6F4

Cat no : 67586-1-Ig

Synonyms

A T mutated, AT1, ATA, ataxia telangiectasia mutated, ATC, ATD, ATDC, ATE, ATM, DKFZp781A0353, Serine protein kinase ATM, TEL1, TELO1



Tested Applications

Positive WB detected inHeLa cells, HSC-T6 cells, HEK-293 cells, HepG2 cells
Positive IF detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

67586-1-Ig targets ATM in WB, IF, ELISA applications and shows reactivity with Human, Rat samples.

Tested Reactivity Human, Rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ATM fusion protein Ag30001
Full Name ataxia telangiectasia mutated
Observed molecular weight 350 kDa
GenBank accession numberBC137169
Gene symbol ATM
Gene ID (NCBI) 472
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is involved in mitogenic signal transduction, meiotic recombination, detection of DNA damage, and cell cycle control.

Protocols

Product Specific Protocols
WB protocol for ATM antibody 67586-1-IgDownload protocol
IF protocol for ATM antibody 67586-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols