Amylin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22305-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human

Positive IHC detected in:
human pancreas tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
islet amyloid polypeptide

Calculated molecular weight:
10 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IAPP

Synonyms
Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide
Background

IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.


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