BMI1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66161-1-Ig |CloneNo.: 2E10A11

Featured Product KD/KO validated

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Con: 86 μg/150 μl

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Species specificity:
human, mouse, monkey

Positive WB detected in:
U-937 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
COS-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
BMI1 polycomb ring finger oncogene

Calculated molecular weight:
37 kDa

Observed molecular weight:
37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BMI1

Synonyms
BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Background

BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.


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