CD1d Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66257-1-Ig |CloneNo.: 1C12F1

Featured Product KD/KO validated

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Freight/Packing

Con: 300 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human testis tissue, Jurkat

Positive IHC detected in:
human skin tissue, human skin tissue, human small intestine tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD1d molecule

Calculated molecular weight:
335aa,38 kDa

Observed molecular weight:
40 kDa, 50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD1D

Synonyms
CD1A, CD1D, CD1d molecule, R3, R3G1
Background

CD1d is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. CD1d is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on NKT cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines. The molecular weight of unglycosylated CD1d is 38 kDa, while glycosylated form of CD1d is 48-55 kDa.


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