CDC25B Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10644-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse liver tissue, Jurkat cells, mouse brain tissue, mouse liver tissue, Raji cells

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cell division cycle 25 homolog B (S. pombe)

Calculated molecular weight:
65 kDa

Observed molecular weight:
60-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDC25B

Synonyms
CDC25B, CDC25HU2, M phase inducer phosphatase 2
Background

CDC25B, also named as CDC25HU2, belongs to the MPI phosphatase family. It is a tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. CDC25B directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. In Jurkat cell, this antibody recognized 2 bands: 60kd(isoform 2, CDC25B2) and 70kd(isoform 4 of CDC25B).


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