COX2/ Cyclooxygenase 2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66351-1-Ig |CloneNo.: 3G2B9

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Con: 150 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
LPS treated HeLa cells, LPS treated RAW 264.7 cells

Positive IHC detected in:
human lung cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:400

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Calculated molecular weight:
604aa,68 kDa

Observed molecular weight:
66-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PTGS2

Synonyms
COX 2, COX2, COX2/ Cyclooxygenase 2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
Background

COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ).


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