DEPDC6 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21312-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 31 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human

Positive WB detected in:
HeLa cells, COLO 320 cells, HT-1080 cells

Positive IHC detected in:
human thyroid cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
DEP domain containing 6

Calculated molecular weight:
409aa,46 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DEPDC6

Synonyms
DEP domain containing 6, DEP.6, DEPDC6, Deptor, DKFZp564B1778, FLJ12341, FLJ12428, FLJ13854
Background

DEPTOR, also named as DEPDC6, is a negative regulator of the mTORC1 and mTORC2 signaling pathways. Through mTOR interactions, DEPTOR is implicated in pathways for cell growth and differentiation, as well as cell-cycle prolongation or termination. It inhibits the kinase activity of both complexes. The MW will migrate to 50-55 kDa with phospho- form.


Back
to top