Showing 1- [1] of [1] Publications
Author: | Haiqing Zhang | |
Pubmed ID: | 31424425 | |
Journal: | J Clin Invest | |
Title: | TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation. | |
Application: | IF | |
Species: | human |
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Early endosome antigen 1 (EEA1) is a marker of early endosomes and has an important role in endosomal trafficking. EEA1 contains coiled-coil regions and an FYVE-type zinc finger which interacts with phosphatidylinositol-3-phosphate. EEA1 functions as a Rab5 effector, mediates endosome docking and, together with SNAREs, leads to membrane fusion.