EIF2C1-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19690-1-AP

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Freight/Packing

Con: 59 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HEK-293 cells, HeLa cells, Jurkat cells, K-562 cells, NIH/3T3 cells

Positive IHC detected in:
human cervical cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
eukaryotic translation initiation factor 2C, 1

Calculated molecular weight:
97 kDa

Observed molecular weight:
97 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EIF2C1

Synonyms
AGO1, Argonaute1, DKFZp686M13167, eIF 2C 1, EIF2C, eIF2C 1, EIF2C1, GERP95, hAgo1, Protein argonaute 1, Q99
Background

EIF2C1, also named as AGO1, belongs to the argonaute family and Ago subfamily. EIF2C1 is required for RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. EIF2C1 may also be required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). The antibody is specific to EIF2C1.


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