EPCAM Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 21050-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, MCF-7 cells, mouse colon tissue

Positive IHC detected in:
human breast cancer tissue, human colon cancer tissue, human stomach cancer tissue, human colon tissue, human lung cancer tissue

Positive IF detected in:
A431 cells, human colon cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
epithelial cell adhesion molecule

Calculated molecular weight:
314aa,35 kDa

Observed molecular weight:
40 kDa,45-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EPCAM

Synonyms
CD326, CO 17A, CO17 1A, EGP, EGP 2, EGP314, EGP34, EGP40, Ep CAM, EPCAM, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733 2, hEGP 2, hEGP314, KS 1/4 antigen, KS1/4, KSA, M1S2, M4S1, MIC18, MK 1, TACST 1, TACSTD1, TROP1
Background

Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. (PMID: 20837599; 19249674; 21576002; 22647938)


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