GABARAP Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 18723-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human placenta tissue, A549 cells, HeLa cells, human heart tissue, mouse brain tissue, mouse liver tissue, mouse pancreas tissue, mouse skeletal muscle tissue

Positive IF detected in:
Starvation treated HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
GABA(A) receptor-associated protein

Calculated molecular weight:
14 kDa

Observed molecular weight:
14 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GABARAP

Synonyms
FLC3B, FLJ25768, GABARAP, MM46
Background

GABARAP (Gamma-aminobutyric acid type A receptor-associated protein), was initially identified as GABAA receptor binding protein and has shown to be implicated in intracellular trafficking of GABAA receptors. Through interacting with a broad rang of proteins, GABARAP has been demonstrated as a multifunctional protein implicated in intracellular vesicle trafficking, apoptosis, and autophagy. The protein level of lipidated form of GABARAP (GABARAP-II) is upregulated during the autophagic process, which makes it as an autophagic marker. This antibody detected endogenous GABARAP protein in lysates from various tissues. It may cross-react with GABARAPL1 due to the high identity of amino acid sequence.


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