NeutraKine™ GM-CSF Monoclonal antibody
NeutraKine™ GM-CSF Monoclonal Antibody for Neutralization,ELISA
Host / Isotype
Mouse / IgG1
Cat no : 69003-1-Ig
|Neutralization||Measured by its ability to neutralize Human GM-CSF induced proliferation of TF-1 cell line (human erythroleukemic cell line). The half neutralization dose (ND50) is typically 1.5-4 μg/mL in the presence of 0.2 ng/mL Human GM-CSF.|
69003-1-Ig targets NeutraKine™ GM-CSF in Neutralization,ELISA applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||human Humankine GM-CSF protein HZ-1002|
|Full Name||colony stimulating factor 2 (granulocyte-macrophage)|
|Gene ID (NCBI)||1437|
|Purification Method||Protein G purification|
|Storage Buffer||Sterile PBS.|
|Reconstitution||This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.|
|Stability and Storage||Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.|
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts. GM-CSF is a hematopoietic growth factor that stimulates the development of early erythroid megakaryocytic and eosinophilic progenitor cells (PMID 2990035). GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes (PMID 3021817, 2984574, 6390681).
This antibody is used to Block/Neutralize GM-CSF protein.