GMDS Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15442-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HeLa cells, rat spleen tissue

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GDP-mannose 4,6-dehydratase

Calculated molecular weight:
42 kDa

Observed molecular weight:
40-42 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GMDS

Synonyms
GDP D mannose dehydratase, GDP mannose 4,6 dehydratase, GMD, GMDS, SDR3E1
Background

GDP-D-mannose-4,6-dehydratase (GMDS) is the key enzyme in the ‘de novo’ pathway of GDP-L-fucose biosynthesis(PMID:10462046). The enzyme is also named as GMD and belongs to the GDP-mannose 4,6-dehydratase family. The gene encodes a 42 kDa protein that catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor.


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